prdc antikoerper, zgc:112207 antikoerper, RGD1560008 antikoerper, Gremlin2 antikoerper, Prdc antikoerper, CKTSF1B2 antikoerper, DAND3 antikoerper, PRDC antikoerper, gremlin 2, DAN family BMP antagonist antikoerper, gremlin 2, DAN family BMP antagonist b antikoerper, gremlin 2, cysteine knot superfamily antikoerper, GREM2 antikoerper, grem2b antikoerper, grem2 antikoerper, Grem2 antikoerper
Hintergrund
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.