Calsyntenin 1 Antikörper

Produktnummer ABIN6292389

Produktdetails anti-Calsyntenin 1 Antikörper

Target: Calsyntenin 1 (CLSTN1)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calsyntenin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CLSTN1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Kommentare:

Expressed in the brain and, a lower level, in the heart, skeletal muscle, kidney and placenta, Accumulates in dystrophic neurites around the amyloid core of Alzheimer disease senile plaques (at protein level)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu Calsyntenin 1

Target: Calsyntenin 1 (CLSTN1)

Andere Bezeichnung: CLSTN1 (CLSTN1 Produkte)

Synonyme: CALSYNTENIN-1 antikoerper, fm67g03 antikoerper, wu:fk52g02 antikoerper, wu:fm67g03 antikoerper, zgc:153744 antikoerper, zgc:56528 antikoerper, clstn1 antikoerper, 1810034E21Rik antikoerper, Cst-1 antikoerper, Cstn1 antikoerper, ALC-ALPHA antikoerper, CDHR12 antikoerper, CSTN1 antikoerper, PIK3CD antikoerper, XB31alpha antikoerper, alcalpha1 antikoerper, alcalpha2 antikoerper, calsyntenin 1 antikoerper, calsyntenin 3 antikoerper, beta-catenin-interacting protein 1 antikoerper, calsyntenin-1 antikoerper, CLSTN1 antikoerper, clstn1 antikoerper, clstn3 antikoerper, LOC100356725 antikoerper, LOC100435584 antikoerper, Clstn1 antikoerper, LOC479600 antikoerper

Hintergrund: This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 109.793 kDa

Gen-ID: 22883

UniProt: O94985