Calsyntenin 1 Antikörper (N-Term)

Produktnummer ABIN1539080

Produktdetails anti-Calsyntenin 1 Antikörper

Target: Calsyntenin 1 (CLSTN1)

Bindungsspezifität: AA 15-42, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calsyntenin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLSTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human CLSTN1.

Klon: RB38737

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CLSTN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu Calsyntenin 1

Target: Calsyntenin 1 (CLSTN1)

Andere Bezeichnung: CLSTN1 (CLSTN1 Produkte)

Synonyme: CALSYNTENIN-1 antikoerper, fm67g03 antikoerper, wu:fk52g02 antikoerper, wu:fm67g03 antikoerper, zgc:153744 antikoerper, zgc:56528 antikoerper, clstn1 antikoerper, 1810034E21Rik antikoerper, Cst-1 antikoerper, Cstn1 antikoerper, ALC-ALPHA antikoerper, CDHR12 antikoerper, CSTN1 antikoerper, PIK3CD antikoerper, XB31alpha antikoerper, alcalpha1 antikoerper, alcalpha2 antikoerper, calsyntenin 1 antikoerper, calsyntenin 3 antikoerper, beta-catenin-interacting protein 1 antikoerper, calsyntenin-1 antikoerper, CLSTN1 antikoerper, clstn1 antikoerper, clstn3 antikoerper, LOC100356725 antikoerper, LOC100435584 antikoerper, Clstn1 antikoerper, LOC479600 antikoerper

Hintergrund: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity).

Molekulargewicht: 109793

Gen-ID: 22883

NCBI Accession: NP_001009566, NP_055759

UniProt: O94985