CCNDBP1 Antikörper

Produktnummer ABIN6291864

Produktdetails anti-CCNDBP1 Antikörper

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCNDBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CCNDBP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Ubiquitously expressed, Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu CCNDBP1

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Andere Bezeichnung: CCNDBP1 (CCNDBP1 Produkte)

Synonyme: CCNDBP1 antikoerper, dip1 antikoerper, gcip antikoerper, DIP1 antikoerper, GCIP antikoerper, HHM antikoerper, AU022347 antikoerper, Maid antikoerper, SECC-8 antikoerper, SSEC-8 antikoerper, cyclin D1 binding protein 1 antikoerper, cyclin D-type binding-protein 1 antikoerper, CCNDBP1 antikoerper, ccndbp1 antikoerper, Ccndbp1 antikoerper

Hintergrund: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.

Molekulargewicht: 40.262 kDa

Gen-ID: 23582

UniProt: O95273