CCNDBP1 Antikörper (C-Term)

Produktnummer ABIN2856378

Produktdetails anti-CCNDBP1 Antikörper

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCNDBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to CCNDBP1 (cyclin D-type binding-protein 1)
CCNDBP1 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CCNDBP1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: CCNDBP1 transfected 293T

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu CCNDBP1

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Andere Bezeichnung: cyclin D1 binding protein 1 (CCNDBP1 Produkte)

Synonyme: CCNDBP1 antikoerper, dip1 antikoerper, gcip antikoerper, DIP1 antikoerper, GCIP antikoerper, HHM antikoerper, AU022347 antikoerper, Maid antikoerper, SECC-8 antikoerper, SSEC-8 antikoerper, cyclin D1 binding protein 1 antikoerper, cyclin D-type binding-protein 1 antikoerper, CCNDBP1 antikoerper, ccndbp1 antikoerper, Ccndbp1 antikoerper

Hintergrund: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.

Cellular Localization: Cytoplasm , Nucleus

Molekulargewicht: 40 kDa

Gen-ID: 23582

UniProt: O95273