UPK1A Antikörper

Produktnummer ABIN6291372

Produktdetails anti-UPK1A Antikörper

Target: UPK1A (Uroplakin 1a (UPK1A))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UPK1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human UPK1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

High expression restricted to ureteric urothelium (most superficial cells)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Andere Bezeichnung: UPK1A (UPK1A Produkte)

Synonyme: up1a antikoerper, upia antikoerper, upka antikoerper, tspan21 antikoerper, MGC81390 antikoerper, upk1a antikoerper, MGC69509 antikoerper, UPK1A antikoerper, wu:fb14a02 antikoerper, wu:fk84c04 antikoerper, zgc:136832 antikoerper, TSPAN21 antikoerper, UP1A antikoerper, UPIA antikoerper, UPKA antikoerper, 1110031P12Rik antikoerper, AU019298 antikoerper, C87192 antikoerper, Tspan21 antikoerper, Upk1 antikoerper, uroplakin 1A antikoerper, uroplakin 1A L homeolog antikoerper, uroplakin 1a antikoerper, UPK1A antikoerper, upk1a.L antikoerper, upk1a antikoerper, Upk1a antikoerper

Hintergrund: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene.

Molekulargewicht: 28.879 kDa

Gen-ID: 11045

UniProt: O00322