UPK1A Antikörper (C-Term)

Produktnummer ABIN955479

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-UPK1A Antikörper (ABIN955479) detektiert spezifisch UPK1A in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für UPK1A Antikörper (C-Term) (ABIN955479)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UPK1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-UPK1A Antikörper

Bindungsspezifität: AA 197-227, C-Term

Spezifität: This antibody detects Uroplakin-1a (UPK1A) (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 197~227 amino acids from the C-terminal region of human UPK1A

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Referenzen für anti-UPK1A Antikörper (ABIN955479)

Feenstra, Thøgersen, Wieser, Peschel, Ball, Brandes, Satchell, Stockner, Aarestrup, Rees, Kain: "Adhesion of Escherichia coli under flow conditions reveals potential novel effects of FimH mutations." in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, Vol. 36, Issue 3, pp. 467-478, (2017) (PubMed).

Details zu UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Andere Bezeichnung: Uroplakin-1a (UPK1A)

Hintergrund: The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.Synonyms: TSPAN21, Tetraspanin-21, Tspan-21, UP1a, UPIa, UPKa, Uroplakin Ia

Gen-ID: 11045

NCBI Accession: NP_008931