PEG3 Antikörper

Produktnummer ABIN6290778

Produktdetails anti-PEG3 Antikörper

Target: PEG3 (Paternally Expressed 3 (PEG3))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PEG3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Brain, glial cells, astrocytes, embryo, placenta, testis, ovary and uterus, In the placenta it is found in the layer of villous cytotrophoblast cells while in the ovary it is found in the cells of the ovarian stroma including the thecal layers around the follicles, Expression is highly repressed in glioma cell lines

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Andere Bezeichnung: PEG3 (PEG3 Produkte)

Synonyme: PW1 antikoerper, ZKSCAN22 antikoerper, ZNF904 antikoerper, ZSCAN24 antikoerper, AL022617 antikoerper, ASF-1 antikoerper, End4 antikoerper, Gcap4 antikoerper, Pw1 antikoerper, Zfp102 antikoerper, mKIAA0287 antikoerper, PEG3 antikoerper, paternally expressed 3 antikoerper, paternally-expressed gene 3 protein antikoerper, PEG3 antikoerper, Peg3 antikoerper, LOC100448879 antikoerper

Hintergrund: In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 180.827 kDa

Gen-ID: 5178

UniProt: Q9GZU2