PEG3 Antikörper (C-Term)

Produktnummer ABIN2780754

Produktdetails anti-PEG3 Antikörper

Target: PEG3 (Paternally Expressed 3 (PEG3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FGECSGYIER ASTSTGGANQ ADEKYFKCDV CGQLFNDRLS LARHQNTHTG

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PEG3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1588 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Andere Bezeichnung: PEG3 (PEG3 Produkte)

Synonyme: PW1 antikoerper, ZKSCAN22 antikoerper, ZNF904 antikoerper, ZSCAN24 antikoerper, AL022617 antikoerper, ASF-1 antikoerper, End4 antikoerper, Gcap4 antikoerper, Pw1 antikoerper, Zfp102 antikoerper, mKIAA0287 antikoerper, PEG3 antikoerper, paternally expressed 3 antikoerper, paternally-expressed gene 3 protein antikoerper, PEG3 antikoerper, Peg3 antikoerper, LOC100448879 antikoerper

Hintergrund: PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: PEG3, ALB, USP7, TRAF2, SIAH2, SIAH1, BRCA1,
Protein Size: 1588

Molekulargewicht: 181 kDa

Gen-ID: 5178

NCBI Accession: NM_006210, NP_006201

UniProt: Q9GZU2