PGK1 Antikörper

Produktnummer ABIN6290734

Produktdetails anti-PGK1 Antikörper

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PGK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Kommentare:

Mainly expressed in spermatogonia, Localized on the principle piece in the sperm (at protein level), Expression significantly decreased in the testis of elderly men

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu PGK1

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Andere Bezeichnung: PGK1 (PGK1 Produkte)

Synonyme: MIG10 antikoerper, PGKA antikoerper, Pgk-1 antikoerper, Pgk antikoerper, PGK antikoerper, wu:fd59b07 antikoerper, wu:fj36g06 antikoerper, zgc:56252 antikoerper, zgc:77899 antikoerper, PGK1 antikoerper, phosphoglycerate kinase 1 antikoerper, pgk2 antikoerper, pgka antikoerper, phosphoglycerate kinase 1 antikoerper, phosphoglycerate kinase 1 L homeolog antikoerper, PGK1 antikoerper, Pgk1 antikoerper, pgk1 antikoerper, LOC100348124 antikoerper, pgk1.L antikoerper

Hintergrund: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.

Molekulargewicht: 44.615 kDa

Gen-ID: 5230

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process