PGK1 Antikörper (AA 305-334)

Produktnummer ABIN391250

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-PGK1 Antikörper wird verwendet zum Nachweis von PGK1 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für PGK1 Antikörper (AA 305-334) (ABIN391250)

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB5517

Produktdetails anti-PGK1 Antikörper

Bindungsspezifität: AA 305-334

Homologie: Pr

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human PGK1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-PGK1 Antikörper (ABIN391250)

Garzón, Gayarre, Gharbi, Díez-Dacal, Sánchez-Gómez, Timms, Pérez-Sala: "A biotinylated analog of the anti-proliferative prostaglandin A1 allows assessment of PPAR-independent effects and identification of novel cellular targets for covalent modification." in: Chemico-biological interactions, Vol. 183, Issue 1, pp. 212-21, (2009) (PubMed).

Details zu PGK1

Target: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Andere Bezeichnung: PGK1

Hintergrund: Also known as ATP:3-phosphoglycerate 1-phosphotransferase, this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. Phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and is proposed to participate in the angiogenic process as a disulfide reductase. Mutations in PGK1 may be associated with hemolytic anemia.

Molekulargewicht: 44615

Gen-ID: 5230

NCBI Accession: NP_000282

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process