CLDN14 Antikörper

Produktnummer ABIN6290241

Produktdetails anti-CLDN14 Antikörper

Target: CLDN14 (Claudin 14 (CLDN14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CLDN14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Liver, kidney, Also found in ear

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu CLDN14

Target: CLDN14 (Claudin 14 (CLDN14))

Andere Bezeichnung: CLDN14 (CLDN14 Produkte)

Synonyme: claudin-14 antikoerper, CLDN14 antikoerper, DFNB29 antikoerper, AI851731 antikoerper, claudin 14 L homeolog antikoerper, claudin 14 antikoerper, cldn14.L antikoerper, CLDN14 antikoerper, Cldn14 antikoerper

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 25.699 kDa

Gen-ID: 23562

UniProt: O95500

Pathways: Cell-Cell Junction Organization, Hepatitis C