CLDN14 Produkte
(Claudin 14 (CLDN14))
Kategorien
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010].
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Ausgewählte CLDN14 Kategorien
CLDN14 Antikörper
High quality antibodies with extensive validation data.
CLDN14 ELISA Kits
Reliable ELISA kits for a wide range of species.
CLDN14 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CLDN14 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7147891
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN1881208
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (3)
Kat. Nr.
ABIN525258
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CLDN14 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1745293
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1744074
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1742853
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CLDN14 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349593
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349591
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3120231
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CLDN14 Produkten
: "Activation of the Ca(2+)-sensing receptor increases renal claudin-14 expression and urinary Ca(2+) excretion." in: American journal of physiology. Renal physiology, Vol. 304, Issue 6, pp. F761-9, (2013) (PubMed).: "Identification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator." in: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17766-76, (2011) (PubMed).
: "Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density." in: Nature genetics, Vol. 41, Issue 8, pp. 926-30, (2009) (PubMed).
: "Mutation in gap and tight junctions in patients with non-syndromic hearing loss." in: Biochemical and biophysical research communications, Vol. 385, Issue 1, pp. 1-5, (2009) (PubMed).
: "Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29." in: Cell, Vol. 104, Issue 1, pp. 165-72, (2001) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
Synonyme und alternative Namen zu CLDN14
claudin 14 L homeolog (cldn14.L), claudin 14 (CLDN14), claudin 14 (Cldn14), AI851731, claudin-14, CLDN14, DFNB29Bezeichner auf Proteinebene für CLDN14
- claudin 14
- claudin-14
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