CLCN3 Produkte
(Chloride Channel 3 (CLCN3))
Kategorien
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Ausgewählte CLCN3 Kategorien
CLCN3 Antikörper
High quality antibodies with extensive validation data.
CLCN3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CLCN3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN6260874
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, ICC, IF
Validierungen
- (3)
Kat. Nr.
ABIN1027722
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene CLCN3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1349568
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3077940
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3077941
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CLCN3 Produkten
: "CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons." in: Journal of cell science, Vol. 129, Issue 7, pp. 1378-90, (2016) (PubMed).: "Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics." in: Immunity, inflammation and disease, Vol. 2, Issue 4, pp. 205-13, (2015) (PubMed).
: "Chloride-hydrogen antiporters ClC-3 and ClC-5 drive osteoblast mineralization and regulate fine-structure bone patterning in vitro." in: Physiological reports, Vol. 3, Issue 11, (2015) (PubMed).
: "Calcium entry via TRPC1 channels activates chloride currents in human glioma cells." in: Cell calcium, Vol. 53, Issue 3, pp. 187-94, (2013) (PubMed).
: "A quantitative assay for lysosomal acidification rates in human osteoclasts." in: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).
: "Expression and localization of CLC chloride transport proteins in the avian retina." in: PLoS ONE, Vol. 6, Issue 3, pp. e17647, (2011) (PubMed).
Synonyme und alternative Namen zu CLCN3
chloride voltage-gated channel 3 (CLCN3), chloride voltage-gated channel 3 (Clcn3), chloride channel, voltage-sensitive 3 (Clcn3), chloride channel 3 (clcn3), chloride channel protein 3 (PTRG_03131), chloride channel protein 3 (BDBG_05668), chloride channel protein 3 (MCYG_04420), chloride channel, voltage-sensitive 3 (clcn3), chloride channel, voltage-sensitive 3 S homeolog (clcn3.S), ClC-3, clc-3, CLC3, Clc3, clc3, CLCN3, fb78c02, wu:fb78c02Bezeichner auf Proteinebene für CLCN3
- H(+)/Cl(-) exchange transporter 3
- chloride channel 3
- chloride channel protein 3
- chloride transporter ClC-3
- protein kinase C-regulated chloride channel
- clC-3
- chloride channel Clc-3
- Chloride channel protein 3
- H(+)/Cl(-) exchange transporter 3-like
- putative chloride channel ClC-3
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