TUBB2A Antikörper

Produktnummer ABIN6288905

Produktdetails anti-TUBB2A Antikörper

Target: TUBB2A (Tubulin, beta 2A (TUBB2A))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: β II tubulin is a protein encoded by the TUBB2A gene which is approximately 49,9 kDa. β II tubulin is localised to the cytoplasm and cytoskeleton. It is involved in Sertoli-Sertoli cell junction dynamics, development Slit-Robo signalling and the GPCR pathway. Tubulin is the major constituent of microtubules. Microtubules are key participants in processes such as mitosis and intracellular transport and are composed of heterodimers of alpha- and beta-tubulins. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. β II tubulin is expressed in the nervous system, eye, skin and lung. Mutations in the TUBB2A gene may result in lung mucoepidermoid carcinoma. STJ97053 was developed from clone Mix and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous β II tubulin protein.

Spezifität: The antibody detects endogenous β II tubulin protein.

Produktmerkmale: Mouse monoclonal to β II tubulin.

Aufreinigung: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Klon: Mix

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:50000-100000
IP 1:200

Kommentare:

High expression in brain, where it represents 30% of all beta-tubulins.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu TUBB2A

Target: TUBB2A (Tubulin, beta 2A (TUBB2A))

Andere Bezeichnung: beta II tubulin (TUBB2A Produkte)

Synonyme: TUBB antikoerper, TUBB2 antikoerper, dJ40E16.7 antikoerper, M(beta)2 antikoerper, Tubb2 antikoerper, TUBB2A antikoerper, tubb2a antikoerper, zgc:112335 antikoerper, tubulin beta 2A class IIa antikoerper, tubulin, beta 2A class IIA antikoerper, tubulin beta-2A chain antikoerper, tubulin, beta 2A class IIa antikoerper, TUBB2A antikoerper, Tubb2a antikoerper, LOC478701 antikoerper, LOC100079040 antikoerper, LOC100349792 antikoerper, LOC100599614 antikoerper, tubb2 antikoerper

Gen-ID: 7280

UniProt: Q13885

Pathways: Microtubule Dynamics, M Phase