MICU1 Antikörper

Produktnummer ABIN6288547

Produktdetails anti-MICU1 Antikörper

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MICU1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: MICU1 is a protein encoded by the MICU1 gene which is approximately 54,3 kDa. MICU1 is localised to the mitochondrion inner membrane and mitochondrion intermembrane space. It is involved in Ca, cAMP and lipid signalling and is an essential regulator of mitochondrial Ca2+ uptake under basal conditions. It interacts with a mitochondrial inner membrane Ca2+ channel and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. MICU1 is expressed in the nervous system, kidney, muscle, skin and thyroid. Mutations in the MICU1 gene may result in dermatitis. STJ97447 was developed from clone Mix and was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. The antibody detects endogenous MICU1 protein.

Spezifität: The antibody detects endogenous MICU1 protein.

Produktmerkmale: Mouse monoclonal to MICU1.

Aufreinigung: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein

Klon: Mix

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000
IHC 1:100-200

Kommentare:

Expressed in epithelial cell lines. Strongly expressed in epidermal keratinocytes and dermal endothelial cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu MICU1

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Andere Bezeichnung: MICU1 (MICU1 Produkte)

Synonyme: CALC antikoerper, CBARA1 antikoerper, EFHA3 antikoerper, C730016L05Rik antikoerper, Calc antikoerper, Cbara1 antikoerper, mitochondrial calcium uptake 1 antikoerper, MICU1 antikoerper, Micu1 antikoerper

Gen-ID: 10367

UniProt: Q9BPX6