PFKM Antikörper (Internal Region)

Produktnummer ABIN6287047

Produktdetails anti-PFKM Antikörper

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: PFKM is a protein encoded by the PKFM gene which is approximately 85,2 kDa. PFKM is localised to the cytoplasm. It is involved in glucose metabolism, carbon metabolism and AMP-activated protein kinase signalling. It exists as three isozymes which function as subunits of the mammalian tetramer phosphofructokinase. It catalyses the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. PFKM is expressed in the nervous system, muscle, heart, lung and kidney. Mutations in the PFKM gene may result in glycogen storage disease, mcardle disease and phosphoglycerate kinase deficiency. STJ95045 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PFKM protein.

Spezifität: PFKM Polyclonal Antibody detects endogenous levels of PFKM protein.

Produktmerkmale: Rabbit polyclonal to PFKM.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PFKM.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu PFKM

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Andere Bezeichnung: PFKM (PFKM Produkte)

Synonyme: GSD7 antikoerper, PFK-1 antikoerper, PFK1 antikoerper, PFKA antikoerper, PFKX antikoerper, AI131669 antikoerper, PFK-A antikoerper, PFK-M antikoerper, Pfk-4 antikoerper, Pfk4 antikoerper, Pfka antikoerper, Pfkx antikoerper, Pfk-M antikoerper, M-PFK antikoerper, PFKM antikoerper, pfkm antikoerper, zgc:92344 antikoerper, pfk antikoerper, im:7137110 antikoerper, wu:fc58g11 antikoerper, phosphofructokinase, muscle antikoerper, phosphofructokinase, platelet antikoerper, phosphofructokinase, muscle a antikoerper, phosphofructokinase, muscle S homeolog antikoerper, phosphofructokinase, muscle b antikoerper, PFKM antikoerper, Pfkm antikoerper, PFKP antikoerper, pfkma antikoerper, pfkm.S antikoerper, pfkmb antikoerper

Molekulargewicht: 85 kDa

Gen-ID: 5213

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effekt