CEP290 Antikörper (Internal Region)

Produktnummer ABIN6284993

Produktdetails anti-CEP290 Antikörper

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Bindungsspezifität: AA 740-820, Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP290 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Verwendungszweck: CEP290 is a protein encoded by the CEP290 gene which is approximately 290,3 kDa. CEP290 is localised to the cytoplasm. It is involved in regulation of PLK1 activity at G2/M transition, innate immune system and mitotic cell cycle. It is a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. It is involved in the early and late steps of cilia formation. CEP290 is ubiquitously expressed with stronger expression in the placenta. Mutations in the CEP290 gene may result in Joubert syndrome. STJ92224 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CEP290 protein.

Spezifität: CEP290 Polyclonal Antibody detects endogenous levels of CEP290 protein.

Produktmerkmale: Rabbit polyclonal to CEP290.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CEP290

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
ELISA 1:20000

Kommentare:

Ubiquitous. Expressed strongly in placenta and weakly in brain.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Andere Bezeichnung: CEP290 (CEP290 Produkte)

Synonyme: ct87 antikoerper, mks4 antikoerper, rd16 antikoerper, bbs14 antikoerper, jbts5 antikoerper, jbts6 antikoerper, lca10 antikoerper, nphp6 antikoerper, slsn6 antikoerper, sh11ag antikoerper, MGC81471 antikoerper, 3h11ag antikoerper, RGD1311640 antikoerper, BC004690 antikoerper, Nphp6 antikoerper, b2b1454Clo antikoerper, b2b1752Clo antikoerper, im:7145703 antikoerper, im:7147820 antikoerper, 3H11Ag antikoerper, BBS14 antikoerper, CT87 antikoerper, JBTS5 antikoerper, LCA10 antikoerper, MKS4 antikoerper, NPHP6 antikoerper, POC3 antikoerper, SLSN6 antikoerper, centrosomal protein 290 antikoerper, centrosomal protein 290 L homeolog antikoerper, centrosomal protein 290kDa antikoerper, CEP290 antikoerper, cep290.L antikoerper, cep290 antikoerper, Cep290 antikoerper

Molekulargewicht: 290 kDa

Gen-ID: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase