PPARG Antikörper (AA 50-130)
-
- Target Alle PPARG Antikörper anzeigen
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
-
Bindungsspezifität
- AA 50-130
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PPARG Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- PPAR-γ is a protein encoded by the PPARG gene which is approximately 57,6 kDa. PPAR-γ is localised to the cytoplasm and nucleus. It is involved in regulation of lipid metabolism, gene expression, the nuclear receptor transcription pathway and AMP-activated protein kinase signalling. This protein falls under the peroxisome proliferator-activated receptor subfamily. It is a nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once logand activated, the nuclear receptor binds to DNA specific PPAR response elements and modulates the transcription of its target genes, such as acyl-CoA oxidase. PPAR-γ has the highest expression in adipose tissue. Mutations in the PPARG gene may result in diabetes mellitus and is a cardiovascular disease risk factor. STJ95201 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PPAR-γ protein.
- Spezifität
- PPAR-γ Polyclonal Antibody detects endogenous levels of PPAR-γ protein.
- Produktmerkmale
- Rabbit polyclonal to PPAR-γ.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human PPAR-gamma around the non-phosphorylation site of S112.
- Isotyp
- IgG
- Top Product
- Discover our top product PPARG Primärantikörper
-
-
- Applikationshinweise
-
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000 - Kommentare
-
Highest expression in adipose tissue. Lower in skeletal muscle, spleen, heart and liver. Also detectable in placenta, lung and ovary.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- Target
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- Andere Bezeichnung
- PPAR-gamma (PPARG Produkte)
- Synonyme
- PPAR gamma antikoerper, PPARg2 antikoerper, PPARG antikoerper, Nr1c3 antikoerper, PPAR-gamma antikoerper, PPAR-gamma2 antikoerper, PPARgamma antikoerper, PPARgamma2 antikoerper, NR1C3 antikoerper, CIMT1 antikoerper, GLM1 antikoerper, PPARG1 antikoerper, PPARG2 antikoerper, xPPAR-gamma antikoerper, PPAR-GAMMA antikoerper, PPARGAMMA antikoerper, peroxisome proliferator-activated receptor gamma antikoerper, peroxisome proliferator activated receptor gamma antikoerper, peroxisome proliferator activated receptor gamma L homeolog antikoerper, PPARG antikoerper, Pparg antikoerper, pparg.L antikoerper
- Molekulargewicht
- 57 kDa
- Gen-ID
- 5468
- UniProt
- P37231
- Pathways
- MAPK Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
-