AIRE Antikörper (Ser156)
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- Target Alle AIRE Antikörper anzeigen
- AIRE (Autoimmune Regulator (AIRE))
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Bindungsspezifität
- AA 100-180, Ser156
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AIRE Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Verwendungszweck
- Rabbit polyclonal to AIRE-1.
- Spezifität
- AIRE-1 Polyclonal Antibody detects endogenous levels of AIRE-1 protein.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156.
- Isotyp
- IgG
- Top Product
- Discover our top product AIRE Primärantikörper
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- Applikationshinweise
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WB 1:500-1:2000
ELISA 1:5000 - Kommentare
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Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lymph nodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC)(at protein level) . Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- AIRE (Autoimmune Regulator (AIRE))
- Andere Bezeichnung
- AIRE-1 (AIRE Produkte)
- Synonyme
- AIRE1 antikoerper, APECED antikoerper, APS1 antikoerper, APSI antikoerper, PGA1 antikoerper, autoimmune regulator antikoerper, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antikoerper, AaeL_AAEL013794 antikoerper, CpipJ_CPIJ001208 antikoerper, CpipJ_CPIJ001209 antikoerper, AIRE antikoerper, Aire antikoerper
- Molekulargewicht
- 50 kDa
- Gen-ID
- 326
- UniProt
- O43918
- Pathways
- Chromatin Binding
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