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AIRE Produkte

(Autoimmune Regulator (AIRE))
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012].

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Ausgewählte AIRE Kategorien

AIRE Antikörper

High quality antibodies with extensive validation data.

AIRE ELISA Kits

Reliable ELISA kits for a wide range of species.

AIRE Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene AIRE Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (6)
Kat. Nr. ABIN3022515
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC, FACS
Validierungen
  • (8)
Kat. Nr. ABIN184780
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
Applikation WB, IHC
Validierungen
  • (5)
Kat. Nr. ABIN2779777
Menge 100 μL
Datenblatt Datenblatt

Empfohlene AIRE ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965095
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954016
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954017
Menge 96 tests
Datenblatt Datenblatt

Empfohlene AIRE Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3088935
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3137558
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7396196
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren AIRE Produkten

Nakasatomi, Maeshima, Mishima, Ikeuchi, Sakairi, Kaneko, Hiromura, Nojima: "Novel approach for the detection of tubular cell migration into the interstitium during renal fibrosis in rats." in: Fibrogenesis & tissue repair, Vol. 8, pp. 12, (2015) (PubMed).

Suzuki, Suzuki, Nakai, Sembon, Fuchimoto, Onishi: "Transcriptional and histological analyses of the thymic developmental process in the fetal pig." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 63, Issue 2, pp. 215-25, (2014) (PubMed).

Ströbel, Hartmann, Rosenwald, Kalla, Ott, Friedel, Schalke, Kasahara, Tomaru, Marx: "Corticomedullary differentiation and maturational arrest in thymomas." in: Histopathology, Vol. 64, Issue 4, pp. 557-66, (2014) (PubMed).

Jüngling, Liu, Lesting, Coulon, Sosulina, Reinscheid, Pape: "Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor." in: The Journal of physiology, Vol. 590, Issue Pt 16, pp. 3701-17, (2012) (PubMed).

Wei, Akerman, Newey, Pan, Clinch, Jacob, Shen, Wilkins, Ellory: "The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism." in: The Journal of physiology, Vol. 589, Issue Pt 22, pp. 5349-59, (2011) (PubMed).

Yuan, Zhu, Zhou, Chen, Zhu, Ma, He, Tian, Shi: "Role of mast cell activation in inducing microglial cells to release neurotrophin." in: Journal of neuroscience research, Vol. 88, Issue 6, pp. 1348-54, (2010) (PubMed).

Zelano, Berg, Thams, Hailer, Cullheim: "SynCAM1 expression correlates with restoration of central synapses on spinal motoneurons after two different models of peripheral nerve injury." in: The Journal of comparative neurology, Vol. 517, Issue 5, pp. 670-82, (2009) (PubMed).

Niki, Oshikawa, Mouri, Hirota, Matsushima, Yano, Han, Bando, Izumi, Matsumoto, Nakayama, Kuroda, Matsumoto: "Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice." in: The Journal of clinical investigation, Vol. 116, Issue 5, pp. 1292-301, (2006) (PubMed).

Tao, Kupfer, Stewart, Williams-Skipp, Crowell, Patel, Sain, Scheinman: "AIRE recruits multiple transcriptional components to specific genomic regions through tethering to nuclear matrix." in: Molecular immunology, Vol. 43, Issue 4, pp. 335-45, (2005) (PubMed).

Kumar, Laloraya, Wang, Ruan, Davoodi-Semiromi, Kao, She: "The autoimmune regulator (AIRE) is a DNA-binding protein." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 41357-64, (2001) (PubMed).

Synonyme und alternative Namen zu AIRE

autoimmune regulator (AaeL_AAEL013794), autoimmune regulator (CpipJ_CPIJ001208), autoimmune regulator (CpipJ_CPIJ001209), autoimmune regulator (AIRE), autoimmune regulator (Aire), autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) (Aire), AIRE1, APECED, APS1, APSI, PGA1

Bezeichner auf Proteinebene für AIRE

  • autoimmune regulator
  • autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein
  • autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • APECED protein homolog
  • autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog
  • autoimmune regulator AIRE1a
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