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NGFR Antikörper (Internal Region)

NGFR Reaktivität: Human, Ratte, Maus WB, IF, ELISA, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6277081
  • Target Alle NGFR Antikörper anzeigen
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Bindungsspezifität
    • 16
    • 13
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 168
    • 61
    • 55
    • 29
    • 27
    • 26
    • 26
    • 21
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 93
    • 82
    • 4
    • 1
    Kaninchen
    Klonalität
    • 100
    • 80
    Polyklonal
    Konjugat
    • 93
    • 15
    • 13
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NGFR Antikörper ist unkonjugiert
    Applikation
    • 109
    • 87
    • 62
    • 59
    • 49
    • 30
    • 27
    • 21
    • 21
    • 14
    • 14
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Spezifität
    NGFR Antibody detects endogenous levels of total NGFR.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human NGFR, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product NGFR Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Andere Bezeichnung
    NGFR (NGFR Produkte)
    Synonyme
    ngfr antikoerper, wu:fb38c02 antikoerper, wu:fc10h01 antikoerper, CD271 antikoerper, Gp80-LNGFR antikoerper, TNFRSF16 antikoerper, p75(NTR) antikoerper, p75NTR antikoerper, LNGFR antikoerper, RNNGFRR antikoerper, Tnfrsf16 antikoerper, p75 antikoerper, NRH1b antikoerper, fullback antikoerper, nrh1 antikoerper, p75ntr antikoerper, tnfrsf16 antikoerper, p75NGFR antikoerper, nerve growth factor receptor antikoerper, neurotrophin receptor associated death domain antikoerper, nerve growth factor receptor S homeolog antikoerper, nerve growth factor receptor (TNFR superfamily, member 16) antikoerper, NGFR antikoerper, nradd antikoerper, Ngfr antikoerper, ngfr.S antikoerper
    Hintergrund

    Description: Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

    Gene: NGFR

    Molekulargewicht
    45kDa
    Gen-ID
    4804
    UniProt
    P08138
    Pathways
    NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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