ATP6V0D1 Antikörper (Internal Region)

Produktnummer ABIN6265939

Produktdetails anti-ATP6V0D1 Antikörper

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V0D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: ATP6V0D1 Antibody detects endogenous levels of total ATP6V0D1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ATP6V0D1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ATP6V0D1

Target: ATP6V0D1 (ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D1 (ATP6V0D1))

Andere Bezeichnung: ATP6V0D1 (ATP6V0D1 Produkte)

Synonyme: ATP6D antikoerper, ATP6DV antikoerper, P39 antikoerper, VATX antikoerper, VMA6 antikoerper, VPATPD antikoerper, AI267038 antikoerper, Ac39 antikoerper, Atp6d antikoerper, Vma6 antikoerper, fb73h07 antikoerper, wu:fb73h07 antikoerper, zgc:63769 antikoerper, ATPase H+ transporting V0 subunit d1 antikoerper, ATPase, H+ transporting, lysosomal V0 subunit D1 antikoerper, ATPase, H+ transporting, lysosomal V0 subunit d1 antikoerper, ATP6V0D1 antikoerper, Atp6v0d1 antikoerper, atp6v0d1 antikoerper

Hintergrund:

Description: Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Gene: ATP6V0D1

Molekulargewicht: 40 kDa

Gen-ID: 9114

UniProt: P61421

Pathways: Transition Metal Ion Homeostasis, Proton Transport, ER-Nucleus Signaling, Unfolded Protein Response