TRPC4AP Antikörper (N-Term)

Produktnummer ABIN6265755

Produktdetails anti-TRPC4AP Antikörper

Target: TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPC4AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: TRPC4AP Antibody detects endogenous levels of total TRPC4AP.

Homologie: Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TRPC4AP, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TRPC4AP

Target: TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))

Andere Bezeichnung: TRPC4AP (TRPC4AP Produkte)

Synonyme: TRPC4AP antikoerper, MGC130977 antikoerper, 4833429F06Rik antikoerper, D2Ertd113e antikoerper, Trrp4ap antikoerper, mFLJ00177 antikoerper, truss antikoerper, C20orf188 antikoerper, TRRP4AP antikoerper, TRUSS antikoerper, transient receptor potential cation channel subfamily C member 4 associated protein antikoerper, transient receptor potential cation channel, subfamily C, member 4 associated protein L homeolog antikoerper, transient receptor potential cation channel, subfamily C, member 4 associated protein antikoerper, TRPC4AP antikoerper, trpc4ap.L antikoerper, trpc4ap antikoerper, Trpc4ap antikoerper

Hintergrund:

Description: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca2+ storage reduction in response to CHRM1.

Gene: TRPC4AP

Molekulargewicht: 91 kDa

Gen-ID: 26133

UniProt: Q8TEL6