TRPC4AP Antikörper (N-Term)

Produktnummer ABIN1539407

Produktdetails anti-TRPC4AP Antikörper

Target: TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))

Bindungsspezifität: AA 49-75, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPC4AP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRPC4AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-75 amino acids from the N-terminal region of human TRPC4AP.

Klon: RB38628

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TRPC4AP Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu TRPC4AP

Target: TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))

Andere Bezeichnung: TRPC4AP (TRPC4AP Produkte)

Synonyme: TRPC4AP antikoerper, MGC130977 antikoerper, 4833429F06Rik antikoerper, D2Ertd113e antikoerper, Trrp4ap antikoerper, mFLJ00177 antikoerper, truss antikoerper, C20orf188 antikoerper, TRRP4AP antikoerper, TRUSS antikoerper, transient receptor potential cation channel subfamily C member 4 associated protein antikoerper, transient receptor potential cation channel, subfamily C, member 4 associated protein L homeolog antikoerper, transient receptor potential cation channel, subfamily C, member 4 associated protein antikoerper, TRPC4AP antikoerper, trpc4ap.L antikoerper, trpc4ap antikoerper, Trpc4ap antikoerper

Hintergrund: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Molekulargewicht: 90852

Gen-ID: 26133

NCBI Accession: NP_056453, NP_955400

UniProt: Q8TEL6