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TINF2 Antikörper (Internal Region)

TIN2 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265586
  • Target Alle TINF2 (TIN2) Antikörper anzeigen
    TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 16
    • 5
    Kaninchen
    Klonalität
    • 17
    • 4
    Polyklonal
    Konjugat
    • 17
    • 2
    • 1
    • 1
    Dieser TINF2 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 12
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    TINF2 Antibody detects endogenous levels of total TINF2.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TINF2, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
    Andere Bezeichnung
    TINF2 (TIN2 Produkte)
    Synonyme
    DKCA3 antikoerper, TIN2 antikoerper, AW552114 antikoerper, D14Wsu146e antikoerper, Tin2 antikoerper, TERF1 interacting nuclear factor 2 antikoerper, Terf1 (TRF1)-interacting nuclear factor 2 antikoerper, TINF2 antikoerper, Tinf2 antikoerper
    Hintergrund

    Description: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

    Gene: TINF2

    Molekulargewicht
    53kDa
    Gen-ID
    26277
    UniProt
    Q9BSI4
    Pathways
    Zellzyklus, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
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