SPARC Antikörper (Internal Region)

Produktnummer ABIN6265253

Produktdetails anti-SPARC Antikörper

Target: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPARC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: SPARC Antibody detects endogenous levels of total SPARC.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SPARC, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SPARC

Target: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Andere Bezeichnung: SPARC (SPARC Produkte)

Synonyme: ON antikoerper, AA517111 antikoerper, BM-40 antikoerper, hm:zeh0062 antikoerper, SPARC antikoerper, sparc antikoerper, secreted protein acidic and cysteine rich antikoerper, secreted acidic cysteine rich glycoprotein antikoerper, secreted protein, acidic, cysteine-rich (osteonectin) antikoerper, secreted protein, acidic, cysteine-rich (osteonectin) L homeolog antikoerper, secreted protein, acidic, cysteine-rich (osteonectin) S homeolog antikoerper, SPARC antikoerper, Sparc antikoerper, sparc antikoerper, sparc.L antikoerper, sparc.S antikoerper

Hintergrund:

Description: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites, an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.

Gene: SPARC

Molekulargewicht: 35kDa

Gen-ID: 6678

UniProt: P09486

Pathways: Autophagie