SLC8A1 Antikörper (Internal Region)

Produktnummer ABIN6265150

Produktdetails anti-SLC8A1 Antikörper

Target: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC8A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: SLC8A1 Antibody detects endogenous levels of total SLC8A1.

Homologie: Pig,Bovine,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SLC8A1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SLC8A1

Target: SLC8A1 (Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))

Andere Bezeichnung: SLC8A1 (SLC8A1 Produkte)

Synonyme: NCX1 antikoerper, AI852629 antikoerper, AV344025 antikoerper, D930008O12Rik antikoerper, Ncx1 antikoerper, Ncx antikoerper, SLC8A1 antikoerper, ncx1n antikoerper, solute carrier family 8 member A1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1 antikoerper, solute carrier family 8 (sodium/calcium exchanger), member 1b antikoerper, sodium/calcium exchanger 1 antikoerper, SLC8A1 antikoerper, Slc8a1 antikoerper, slc8a1b antikoerper, Tsp_07038 antikoerper

Hintergrund:

Description: Mediates the exchange of one Ca2+ ion against three to four Na+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca2+ levels and Ca2+-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca2+ transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca2+ levels due to release of Ca2+ stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca2+ from the cell during the next phase, so that cytoplasmic Ca2+ levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions.

Gene: SLC8A1

Molekulargewicht: 109kDa

Gen-ID: 6546

UniProt: P32418

Pathways: Myometrial Relaxation and Contraction