PSMD4/ASF Antikörper (Internal Region)

Produktnummer ABIN6264490

Produktdetails anti-PSMD4/ASF Antikörper

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD4/ASF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PSMD4 Antibody detects endogenous levels of total PSMD4.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSMD4, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PSMD4/ASF

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Andere Bezeichnung: PSMD4 (Psmd4 Produkte)

Synonyme: af-1 antikoerper, mcb1 antikoerper, pub-r5 antikoerper, rpn10 antikoerper, PSMD4 antikoerper, DDBDRAFT_0202512 antikoerper, DDBDRAFT_0232981 antikoerper, DDB_0202512 antikoerper, DDB_0232981 antikoerper, AF antikoerper, AF-1 antikoerper, ASF antikoerper, MCB1 antikoerper, Rpn10 antikoerper, S5A antikoerper, pUB-R5 antikoerper, xrpn10c antikoerper, Af1 antikoerper, Mcb1 antikoerper, angiocidin antikoerper, im:6912672 antikoerper, psmd4 antikoerper, wu:fc68c04 antikoerper, zgc:110247 antikoerper, proteasome 26S subunit, non-ATPase 4 antikoerper, 26S proteasome non-ATPase regulatory subunit 4 antikoerper, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antikoerper, proteasome 26S subunit, non-ATPase 4 L homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antikoerper, proteasome 26S subunit, non-ATPase 4b antikoerper, psmd4 antikoerper, PSMD4 antikoerper, LOC100194679 antikoerper, psmD4 antikoerper, LOC100283637 antikoerper, Smp_000740.1 antikoerper, psmd4.L antikoerper, Psmd4 antikoerper, psmd4b antikoerper

Hintergrund:

Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains.

Gene: PSMD4

Molekulargewicht: 41kDa

Gen-ID: 5710

UniProt: P55036

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway