PNKP Antikörper (Internal Region)

Produktnummer ABIN6264320

Produktdetails anti-PNKP Antikörper

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNKP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: PNKP Antibody detects endogenous levels of total PNKP.

Homologie: Pig,Bovine

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PNKP, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Andere Bezeichnung: PNKP (PNKP Produkte)

Synonyme: EIEE10 antikoerper, MCSZ antikoerper, PNK antikoerper, Tb06.28P18.320 antikoerper, 21.m03011 antikoerper, 1810009G08Rik antikoerper, polynucleotide kinase 3'-phosphatase antikoerper, hypothetical protein antikoerper, polynucleotide kinase 3'- phosphatase antikoerper, PNKP antikoerper, Pnkp antikoerper, Tc00.1047053507017.50 antikoerper, Tc00.1047053505807.190 antikoerper, Tb927.6.1580 antikoerper, BBOV_IV000690 antikoerper, CC1G_05202 antikoerper, PGTG_20262 antikoerper, PGTG_18987 antikoerper, pnkp.S antikoerper, pnkp antikoerper

Hintergrund:

Description: Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.

Gene: PNKP

Molekulargewicht: 60kDa

Gen-ID: 11284

UniProt: Q96T60

Pathways: DNA Reparatur, Nucleotide Phosphorylation