PAK6 Antikörper (Internal Region)
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- Target Alle PAK6 Antikörper anzeigen
- PAK6 (P21-Activated Kinase 6 (PAK6))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAK6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- PAK6 Antibody detects endogenous levels of total PAK6.
- Homologie
- Pig,Horse,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PAK6, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PAK6 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- PAK6 (P21-Activated Kinase 6 (PAK6))
- Andere Bezeichnung
- PAK6 (PAK6 Produkte)
- Synonyme
- PAK5 antikoerper, 4732456M09 antikoerper, pak6 antikoerper, si:ch211-158b22.3 antikoerper, p21 (RAC1) activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6b antikoerper, PAK6 antikoerper, Pak6 antikoerper, pak6b antikoerper
- Hintergrund
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Description: Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
Gene: PAK6
- Molekulargewicht
- 75 kDa
- Gen-ID
- 106821730, 56924
- UniProt
- Q9NQU5
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