PAK6 Produkte
(P21-Activated Kinase 6 (PAK6))
Kategorien
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].
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Ausgewählte PAK6 Kategorien
PAK6 Antikörper
High quality antibodies with extensive validation data.
PAK6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PAK6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), IF
Validierungen
- (4)
Kat. Nr.
ABIN656098
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN3032120
Menge
0.4 mL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN528014
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PAK6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6218404
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PAK6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570612
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN5570004
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5570611
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PAK6 Produkten
: "Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein." in: Oncogene, Vol. 37, Issue 13, pp. 1730-1742, (2019) (PubMed).: "Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells." in: Oncotarget, Vol. 7, Issue 38, pp. 61229-61245, (2016) (PubMed).
: "P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3025-35, (2013) (PubMed).
: "Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 7, pp. 3759-66, (2012) (PubMed).
: "Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase." in: The Journal of biological chemistry, Vol. 280, Issue 5, pp. 3323-30, (2005) (PubMed).
: "Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1922-31, (2004) (PubMed).
: "Identification of an autoinhibitory domain of p21-activated protein kinase 5." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 33621-4, (2003) (PubMed).
: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).
: "AR and ER interaction with a p21-activated kinase (PAK6)." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 1, pp. 85-99, (2002) (PubMed).
: "Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain." in: Oncogene, Vol. 21, Issue 24, pp. 3939-48, (2002) (PubMed).
Synonyme und alternative Namen zu PAK6
p21 (RAC1) activated kinase 6 (PAK6), p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), p21 (RAC1) activated kinase 6 (Pak6), p21 protein (Cdc42/Rac)-activated kinase 6b (pak6b), p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), 4732456M09, PAK5, pak6, si:ch211-158b22.3Bezeichner auf Proteinebene für PAK6
- p21(CDKN1A)-activated kinase 6
- serine/threonine-protein kinase PAK 6
- PAK-6
- p21-activated kinase 6
- p21 (CDKN1A)-activated kinase 6
- p21 protein (Cdc42/Rac)-activated kinase 6
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