PAK4 Produkte
(P21-Activated Kinase 4 (PAK4))
Kategorien
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte PAK4 Kategorien
PAK4 Antikörper
High quality antibodies with extensive validation data.
PAK4 ELISA Kits
Reliable ELISA kits for a wide range of species.
PAK4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PAK4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7439984
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7169132
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, FACS
Validierungen
- (5)
Kat. Nr.
ABIN3032118
Menge
0.4 mL
Datenblatt
Datenblatt
Empfohlene PAK4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958368
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN5564605
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1571715
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PAK4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5569703
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN5569960
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5570591
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PAK4 Produkten
: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).: "Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum." in: Journal of virology, Vol. 91, Issue 6, (2017) (PubMed).
: "p21-Activated kinase 4 predicts early recurrence and poor survival in patients with nonmetastatic clear cell renal cell carcinoma." in: Urologic oncology, Vol. 33, Issue 5, pp. 205.e13-21, (2015) (PubMed).
: "p21-Activated kinase 4 promotes prostate cancer progression through CREB." in: Oncogene, Vol. 32, Issue 19, pp. 2475-82, (2013) (PubMed).
: "p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 43, pp. 18622-7, (2010) (PubMed).
: "Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor." in: Molecular and cellular biology, Vol. 29, Issue 11, pp. 3018-32, (2009) (PubMed).
: "Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling." in: Journal of cell science, Vol. 121, Issue Pt 7, pp. 989-1001, (2008) (PubMed).
: "p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD." in: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5526-39, (2003) (PubMed).
: "p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10374-80, (2003) (PubMed).
: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).
Synonyme und alternative Namen zu PAK4
p21 (RAC1) activated kinase 4 (PAK4), p21 protein (Cdc42/Rac)-activated kinase 4 (Pak4), p21 (RAC1) activated kinase 4 (Pak4), p21 protein (Cdc42/Rac)-activated kinase 4 (pak4), 5730488L07Rik, AW555722, im:5916170, mKIAA1142, wu:fd12b01, zgc:92014Bezeichner auf Proteinebene für PAK4
- PAK-4
- p21(CDKN1A)-activated kinase 4
- p21-activated kinase 4
- protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
- serine/threonine-protein kinase PAK 4
- p21 (CDKN1A)-activated kinase 4
- p21 protein (Cdc42/Rac)-activated kinase 4
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