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PAK3 Produkte

(PAK3)

Kategorien

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Ausgewählte PAK3 Kategorien

PAK3 Antikörper

High quality antibodies with extensive validation data.

PAK3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PAK3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN518612
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Monkey
Applikation WB, ELISA, IHC, FACS, ICC, Neut
Validierungen
  • (4)
Kat. Nr. ABIN5611206
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC
Validierungen
  • (5)
Kat. Nr. ABIN3028914
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene PAK3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380787
Menge 2 x 96 tests
Datenblatt Datenblatt

Empfohlene PAK3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf21)
Validierungen
  • (2)
Kat. Nr. ABIN5570580
Menge 5 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (2)
Kat. Nr. ABIN5570579
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313925
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PAK3 Produkten

Wang, Gratzke, Tamalunas, Wiemer, Ciotkowska, Rutz, Waidelich, Strittmatter, Liu, Stief, Hennenberg: "P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153312, (2016) (PubMed).

Valente, Turacchio, Mariggiò, Pagliuso, Gaibisso, Di Tullio, Santoro, Formiggini, Spanò, Piccini, Polishchuk, Colanzi, Luini, Corda: "A 14-3-3? dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII? to regulate post-Golgi carrier formation." in: Nature cell biology, Vol. 14, Issue 4, pp. 343-54, (2012) (PubMed).

Kitano, Schwarz, Nickel, Pääbo: "Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees." in: Molecular biology and evolution, Vol. 20, Issue 8, pp. 1281-9, (2003) (PubMed).

Synonyme und alternative Namen zu PAK3

p21 (RAC1) activated kinase 3 (PAK3), p21 protein (Cdc42/Rac)-activated kinase 3 (Pak3), p21 (RAC1) activated kinase 3 (Pak3), p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog (pak3.L), beta-PAK, bPAK, bpak, CDKN1A, cdkn1a, hPAK3, MRX30, mrx30, MRX47, mrx47, OPHN3, ophn3, PAK-3, pak3, pak3-A, PAK3beta, pak3beta, Pak65alpha, Pak65beta, Stk4, XPak3

Bezeichner auf Proteinebene für PAK3

  • PAK-3
  • beta-PAK
  • oligophrenin-3
  • p21 (CDKN1A)-activated kinase 3
  • p21-activated kinase 3
  • serine/threonine-protein kinase PAK 3
  • CDC42/RAC effector kinase PAK-B
  • p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related)
  • p65-PAK
  • PAK3a protein
  • PAK3d protein
  • serine/threonine protein kinase (p21-activated kinase 3)
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