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PAK1 Produkte

(P21-Activated Kinase 1 (PAK1))

Kategorien

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].

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Ausgewählte PAK1 Kategorien

PAK1 Antikörper

High quality antibodies with extensive validation data.

PAK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PAK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PAK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN2855705
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7442222
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (5)
Kat. Nr. ABIN6145183
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PAK1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380784
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380245
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5593908
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PAK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3132173
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094318
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509057
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PAK1 Produkten

Li, Wang, Peng, Yao, Chen, Tao, Gao, Wang, Li, Cai, Lai, Li, Chen, Huang: "The metastatic promoter DEPDC1B induces epithelial-mesenchymal transition and promotes prostate cancer cell proliferation via Rac1-PAK1 signaling." in: Clinical and translational medicine, Vol. 10, Issue 6, pp. e191, (2020) (PubMed).

Cai, Zhang, Zhang, Chen, Hu: "Effect of Th9/IL-9 on the growth of gastric cancer in nude mice." in: OncoTargets and therapy, Vol. 12, pp. 2225-2234, (2019) (PubMed).

Zhang, Li, Liu, Cao, Chen, Liu, Wang, Du, Weng, Ma: "p21-activated kinase 1 activity is required for histone H3 Ser10 phosphorylation and chromatin condensation in mouse oocyte meiosis." in: Reproduction, fertility, and development, Vol. 29, Issue 7, pp. 1287-1296, (2018) (PubMed).

Tu, Wang, Cui, Wang, Ran, Bao, Lu, Wang, Lydon, DeMayo, Zhang, Kong, Wu, Wang: "Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice." in: Cell death and differentiation, Vol. 23, Issue 1, pp. 169-81, (2016) (PubMed).

El-Baba, Mahadevan, Fahlbusch, S, Rau, Gali-Muhtasib, Schneider-Stock: "Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer." in: Molecular cancer, Vol. 13, pp. 201, (2014) (PubMed).

Chatterjee, Ghosh, Ramdas, Mali, Martin, Kobayashi, Vemula, Canela, Waskow, Visconte, Tiu, Smith, Shah, Bunting, Boswell, Liu, Chan, Kapur: "Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis." in: Cell reports, Vol. 9, Issue 4, pp. 1333-48, (2014) (PubMed).

Nie, Lilley, Pan, Faruque, Liu, Zhang, Sanes, Han, Shi: "SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic ? cells." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2527-34, (2013) (PubMed).

Wang, Ma, Xu, Wang, Zhu, An, An, Wu, Tian: "Phosphorylation of histone H3 on Ser10 by auto-phosphorylated PAK1 is not essential for chromatin condensation and meiotic progression in porcine oocytes." in: Journal of animal science and biotechnology, Vol. 4, Issue 1, pp. 13, (2013) (PubMed).

Geiger, Velic, Macek, Lundberg, Kampf, Nagaraj, Uhlen, Cox, Mann: "Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1709-22, (2013) (PubMed).

Goc, Al-Azayzih, Abdalla, Al-Husein, Kavuri, Lee, Moses, Somanath: "P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3025-35, (2013) (PubMed).

Synonyme und alternative Namen zu PAK1

p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S), p21 (RAC1) activated kinase 1 (PAK1), p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), p21 (RAC1) activated kinase 1 (Pak1), Serine/threonine-protein kinase pak-1 (pak-1), AW045634, pak, pak-1, PAK-1, Paka, pakalpha, PAKalpha, X-PAK1, XPak1

Bezeichner auf Proteinebene für PAK1

  • p21 GTPase-associated kinase 1
  • p21-activated kinase 1
  • p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
  • putative CDKN1A-activated kinase 1
  • STE20 homolog, yeast
  • alpha-PAK
  • p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
  • p65-PAK
  • serine/threonine-protein kinase PAK 1
  • CDC42/RAC effector kinase PAK-A
  • activated protein kinase alpha
  • PAK-1
  • p21 (CDKN1A)-activated kinase 1
  • p68-PAK
  • protein kinase MUK2
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