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PAK1/2/3 Produkte

(P21-Activated Kinases 1/2/3 (PAK1/2/3))

Kategorien

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].

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Ausgewählte PAK1/2/3 Kategorien

PAK1/2/3 Antikörper

High quality antibodies with extensive validation data.

Empfohlene PAK1/2/3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC, ELISA, WB
Validierungen
  • (3)
Kat. Nr. ABIN7180065
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, ELISA, WB
Validierungen
  • (4)
Kat. Nr. ABIN1847964
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, ELISA, IF
Validierungen
  • (2)
Kat. Nr. ABIN7138850
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PAK1/2/3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380246
Menge 2 x 96 tests
Datenblatt Datenblatt

Neueste Publikationen zu unseren PAK1/2/3 Produkten

Babagana, Johnson, Slabodkin, Bshara, Morrison, Kandel: "P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells." in: Molecular carcinogenesis, Vol. 56, Issue 5, pp. 1515-1525, (2017) (PubMed).

Jackson, Weinrich, Woollard: "Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets." in: Scientific reports, Vol. 6, pp. 20038, (2016) (PubMed).

Parsons, Monypenny, Ameer-Beg, Millard, Machesky, Peter, Keppler, Schiavo, Watson, Chernoff, Zicha, Vojnovic, Ng: "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1680-95, (2005) (PubMed).

Lampugnani, Zanetti, Breviario, Balconi, Orsenigo, Corada, Spagnuolo, Betson, Braga, Dejana: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, (2002) (PubMed).

Wang, Mazumdar, Vadlamudi, Kumar: "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium." in: The EMBO journal, Vol. 21, Issue 20, pp. 5437-47, (2002) (PubMed).

Das, Dines, Alapin, Lamprecht: "Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala." in: Scientific reports, Vol. 7, Issue 1, pp. 13930 (PubMed).

Synonyme und alternative Namen zu PAK1/2/3

p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S), p21 (RAC1) activated kinase 1 (PAK1), pak, pak-1, pakalpha, X-PAK1, XPak1

Bezeichner auf Proteinebene für PAK1/2/3

  • p21 GTPase-associated kinase 1
  • p21-activated kinase 1
  • p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
  • putative CDKN1A-activated kinase 1
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