PACS2 Antikörper (Internal Region)

Produktnummer ABIN6264008

Produktdetails anti-PACS2 Antikörper

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: PACS2 Antibody detects endogenous levels of total PACS2.

Homologie: Pig,Bovine,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PACS2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PACS2

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Andere Bezeichnung: PACS2 (PACS2 Produkte)

Synonyme: PACS-2 antikoerper, PACS1L antikoerper, 6720425G15Rik antikoerper, AW208651 antikoerper, AW489976 antikoerper, E230011J22 antikoerper, Pacs1l antikoerper, mKIAA0602 antikoerper, phosphofurin acidic cluster sorting protein 2 antikoerper, PACS2 antikoerper, Pacs2 antikoerper

Hintergrund:

Description: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Gene: PACS2

Molekulargewicht: 116 kDa

Gen-ID: 23241

UniProt: Q86VP3