PACS2 Antikörper (AA 330-380)

Produktnummer ABIN6992140

Produktdetails anti-PACS2 Antikörper

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Bindungsspezifität: AA 330-380

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: PACS2 antibody is human, mouse and rat reactive. At least three isoforms of PACS2 are known to exist, this antibody will detect all three. PACS2 antibody is predicted to not cross-react with PACS1.

Aufreinigung: PACS2 antibody is affinity chromatography purified via peptide column.

Immunogen: PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2. The immunogen is located within amino acids 330 - 380 of PACS2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PACS2 antibody can be used for detection of PACS2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PACS2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PACS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PACS2

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Andere Bezeichnung: PACS2 (PACS2 Produkte)

Synonyme: PACS-2 antikoerper, PACS1L antikoerper, 6720425G15Rik antikoerper, AW208651 antikoerper, AW489976 antikoerper, E230011J22 antikoerper, Pacs1l antikoerper, mKIAA0602 antikoerper, phosphofurin acidic cluster sorting protein 2 antikoerper, PACS2 antikoerper, Pacs2 antikoerper

Hintergrund: PACS2 (phosphofurin acidic cluster sorting protein-2), PACS1L, is an 889 amino acid protein that localizes to both the mitochondrion and the lumen of the endoplasmic reticulum (ER) and belongs to the PACS family (1,2). It is expressed in a broad range of tissues with highest expression in skeletal muscle, brain, heart, testis and pancreas (2,). PACS2 interacts with Polycystin-2 and BID and functions as a sorting protein that regulates mitochondria-ER communication and is thought to be involved in ion channel trafficking, specifically direct cluster-containing ion channels to distinct subcellular compartments (3-5).

Molekulargewicht: Predicted: 98 kDa

Observed: 95 kDa

Gen-ID: 23241

NCBI Accession: NP_056012

UniProt: Q86VP3