SCN9A Antikörper (Internal Region)

Produktnummer ABIN6263503

Produktdetails anti-SCN9A Antikörper

Target: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN9A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: Nav1.7 Antibody detects endogenous levels of total Nav1.7.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Nav1.7, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SCN9A

Target: SCN9A (Sodium Channel, Voltage-Gated, Type IX, alpha Subunit (SCN9A))

Andere Bezeichnung: SCN9A (SCN9A Produkte)

Synonyme: SCN9A antikoerper, DKFZp459G084 antikoerper, Nav1.7 antikoerper, PN1 antikoerper, mKIAA4197 antikoerper, Scn2a antikoerper, ETHA antikoerper, FEB3B antikoerper, GEFSP7 antikoerper, NE-NA antikoerper, NENA antikoerper, SFNP antikoerper, sodium channel, voltage-gated, type IX, alpha subunit antikoerper, sodium voltage-gated channel alpha subunit 9 antikoerper, sodium channel protein type 9 subunit alpha antikoerper, sodium channel, voltage-gated, type IX, alpha antikoerper, SCN9A antikoerper, LOC100016648 antikoerper, Scn9a antikoerper

Hintergrund:

Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient (PubMed:7720699, PubMed:17167479, PubMed:25240195, PubMed:26680203, PubMed:15385606, PubMed:16988069, PubMed:17145499, PubMed:19369487, PubMed:24311784). It is a tetrodotoxin-sensitive Na+ channel isoform (PubMed:7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:17167479, PubMed:17145499, PubMed:19369487, PubMed:24311784).

Gene: SCN9A

Molekulargewicht: 220kDa

Gen-ID: 6335

UniProt: Q15858