KCNJ11 Antikörper (Internal Region)
-
- Target Alle KCNJ11 Antikörper anzeigen
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
-
Bindungsspezifität
- Internal Region
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser KCNJ11 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Kir6.2 Antibody detects endogenous levels of total Kir6.2.
- Homologie
- Bovine,Horse,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Kir6.2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product KCNJ11 Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
-
- Target
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
- Andere Bezeichnung
- KCNJ11 (KCNJ11 Produkte)
- Synonyme
- kir6.2 antikoerper, Kir6.2 antikoerper, mBIR antikoerper, BIR antikoerper, HHF2 antikoerper, IKATP antikoerper, KIR6.2 antikoerper, PHHI antikoerper, TNDM3 antikoerper, potassium voltage-gated channel subfamily J member 11 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 11 antikoerper, potassium inwardly rectifying channel, subfamily J, member 11 antikoerper, KCNJ11 antikoerper, kcnj11 antikoerper, Kcnj11 antikoerper
- Hintergrund
-
Description: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Gene: KCNJ11
- Molekulargewicht
- 44 kDa
- Gen-ID
- 3767
- UniProt
- Q14654
- Pathways
- Negative Regulation of Hormone Secretion
-