IGF2 Antikörper (Internal Region)

Produktnummer ABIN6262492

Produktdetails anti-IGF2 Antikörper

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: IGF2 Antibody detects endogenous levels of total IGF2.

Homologie: Pig,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IGF2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Andere Bezeichnung: IGF2 (IGF2 Produkte)

Synonyme: C11orf43 antikoerper, IGF-II antikoerper, PP9974 antikoerper, LOC100136550 antikoerper, igf2 antikoerper, igf2b antikoerper, wu:fc26e03 antikoerper, zgc:91781 antikoerper, igf-2 antikoerper, insigf antikoerper, pp9974 antikoerper, AL033362 antikoerper, Igf-2 antikoerper, Igf-II antikoerper, M6pr antikoerper, Mpr antikoerper, Peg2 antikoerper, IGFII antikoerper, RNIGF2 antikoerper, IGF-II-B antikoerper, igf2-a antikoerper, igf2-b antikoerper, insulin like growth factor 2 antikoerper, insulin-like growth factor II antikoerper, insulin-like growth factor 2a antikoerper, insulin like growth factor 2 S homeolog antikoerper, insulin-like growth factor 2 antikoerper, insulin-like growth factor 2 (somatomedin A) antikoerper, insulin like growth factor 2 L homeolog antikoerper, IGF2 antikoerper, LOC100136550 antikoerper, igf2a antikoerper, igf2.S antikoerper, Igf2 antikoerper, igf2.L antikoerper

Hintergrund:

Description: The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464).

Gene: IGF2

Molekulargewicht: 20kDa

Gen-ID: 3481

UniProt: P01344

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation