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ICOS Antikörper (Internal Region)

ICOS Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262438
  • Target Alle ICOS Antikörper anzeigen
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    Bindungsspezifität
    • 15
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 91
    • 36
    • 32
    • 6
    Human, Maus, Ratte
    Wirt
    • 71
    • 17
    • 13
    • 2
    • 1
    Kaninchen
    Klonalität
    • 68
    • 36
    Polyklonal
    Konjugat
    • 40
    • 13
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ICOS Antikörper ist unkonjugiert
    Applikation
    • 60
    • 33
    • 30
    • 29
    • 14
    • 13
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    ICOS Antibody detects endogenous levels of total ICOS.
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ICOS, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ICOS Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    Andere Bezeichnung
    ICOS (ICOS Produkte)
    Synonyme
    ICOS antikoerper, AILIM antikoerper, CCLP antikoerper, CRP-1 antikoerper, H4 antikoerper, Ly115 antikoerper, CD278 antikoerper, CVID1 antikoerper, Ailim antikoerper, inducible T-cell costimulator antikoerper, inducible T cell co-stimulator antikoerper, inducible T-cell co-stimulator antikoerper, ICOS antikoerper, LOC100232284 antikoerper, Icos antikoerper
    Hintergrund

    Description: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

    Gene: ICOS

    Molekulargewicht
    23kDa
    Gen-ID
    29851
    UniProt
    Q9Y6W8
    Pathways
    Cancer Immune Checkpoints
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