ICOS Antikörper (Internal Region)
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- Target Alle ICOS Antikörper anzeigen
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ICOS Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- ICOS Antibody detects endogenous levels of total ICOS.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ICOS, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ICOS Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
- Andere Bezeichnung
- ICOS (ICOS Produkte)
- Synonyme
- ICOS antikoerper, AILIM antikoerper, CCLP antikoerper, CRP-1 antikoerper, H4 antikoerper, Ly115 antikoerper, CD278 antikoerper, CVID1 antikoerper, Ailim antikoerper, inducible T-cell costimulator antikoerper, inducible T cell co-stimulator antikoerper, inducible T-cell co-stimulator antikoerper, ICOS antikoerper, LOC100232284 antikoerper, Icos antikoerper
- Hintergrund
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Description: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
Gene: ICOS
- Molekulargewicht
- 23kDa
- Gen-ID
- 29851
- UniProt
- Q9Y6W8
- Pathways
- Cancer Immune Checkpoints
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