GTF2H4 Antikörper (Internal Region)

Produktnummer ABIN6262124

Produktdetails anti-GTF2H4 Antikörper

Target: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2H4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: GTF2H4 Antibody detects endogenous levels of total GTF2H4.

Homologie: Bovine,Sheep,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GTF2H4, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GTF2H4

Target: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Andere Bezeichnung: GTF2H4 (GTF2H4 Produkte)

Synonyme: gtf2h4.2 antikoerper, tfb2 antikoerper, tfiih antikoerper, DDBDRAFT_0191833 antikoerper, DDBDRAFT_0231037 antikoerper, DDB_0191833 antikoerper, DDB_0231037 antikoerper, AW545633 antikoerper, BTF2 p52 antikoerper, TFIIH antikoerper, p44 antikoerper, p52 antikoerper, wu:fa04h09 antikoerper, zgc:77721 antikoerper, P52 antikoerper, TFB2 antikoerper, gtf2h4.1 antikoerper, discoidin domain receptor tyrosine kinase 1 antikoerper, general transcription factor IIH subunit 4 antikoerper, TFIIH subunit antikoerper, valine--tRNA ligase, mitochondrial antikoerper, general transcription factor II H, polypeptide 4 antikoerper, general transcription factor 2H subunit 4 antikoerper, general transcription factor IIH, polypeptide 4 antikoerper, general transcription factor IIH subunit 4 S homeolog antikoerper, general transcription factor IIH, polypeptide 4, 52kDa antikoerper, DDR1 antikoerper, GTF2H4 antikoerper, gtf2h4 antikoerper, LOC100351754 antikoerper, Gtf2h4 antikoerper, gtf2h4.S antikoerper

Hintergrund:

Description: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.

Gene: GTF2H4

Molekulargewicht: 52 kDa

Gen-ID: 2968

UniProt: Q92759

Pathways: DNA Reparatur