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GADD34 Antikörper

PPP1R15A Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261868
  • Target Alle GADD34 (PPP1R15A) Antikörper anzeigen
    GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
    Reaktivität
    • 30
    • 19
    • 18
    • 5
    • 3
    • 3
    • 1
    Human, Maus, Ratte
    Wirt
    • 28
    • 2
    • 2
    Kaninchen
    Klonalität
    • 29
    • 2
    Polyklonal
    Konjugat
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GADD34 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 17
    • 13
    • 13
    • 11
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    GADD34 Antibody detects endogenous levels of total GADD34.
    Homologie
    Pig,Bovine,Horse,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GADD34
    Isotyp
    IgG
    Top Product
    Discover our top product PPP1R15A Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
    Andere Bezeichnung
    PPP1R15A (PPP1R15A Produkte)
    Synonyme
    9630030H21 antikoerper, Gadd34 antikoerper, Myd116 antikoerper, GADD34 antikoerper, Peg-3 antikoerper, RGD1624209 antikoerper, protein phosphatase 1 regulatory subunit 15A antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 15A antikoerper, protein phosphatase 1, regulatory subunit 15A antikoerper, PPP1R15A antikoerper, Ppp1r15a antikoerper
    Hintergrund

    Description: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

    Gene: PPP1R15A

    Molekulargewicht
    100 kDa
    Gen-ID
    23645
    UniProt
    O75807
    Pathways
    ER-Nucleus Signaling, Unfolded Protein Response
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