GADD34 Antikörper
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- Target Alle GADD34 (PPP1R15A) Antikörper anzeigen
- GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GADD34 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- GADD34 Antibody detects endogenous levels of total GADD34.
- Homologie
- Pig,Bovine,Horse,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GADD34
- Isotyp
- IgG
- Top Product
- Discover our top product PPP1R15A Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
- Andere Bezeichnung
- PPP1R15A (PPP1R15A Produkte)
- Synonyme
- 9630030H21 antikoerper, Gadd34 antikoerper, Myd116 antikoerper, GADD34 antikoerper, Peg-3 antikoerper, RGD1624209 antikoerper, protein phosphatase 1 regulatory subunit 15A antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 15A antikoerper, protein phosphatase 1, regulatory subunit 15A antikoerper, PPP1R15A antikoerper, Ppp1r15a antikoerper
- Hintergrund
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Description: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
Gene: PPP1R15A
- Molekulargewicht
- 100 kDa
- Gen-ID
- 23645
- UniProt
- O75807
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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