CYR61 Antikörper (Internal Region)

Produktnummer ABIN6261175

Produktdetails anti-CYR61 Antikörper

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYR61 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: CYR61/CCN1 Antibody detects endogenous levels of total CYR61/CCN1.

Homologie: Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CYR61/CCN1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CYR61

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Andere Bezeichnung: CYR61 (CYR61 Produkte)

Synonyme: CCN1 antikoerper, GIG1 antikoerper, IGFBP10 antikoerper, ccn1 antikoerper, gig1 antikoerper, Xcyr61 antikoerper, igfbp10 antikoerper, MGC69281 antikoerper, MGC69539 antikoerper, cyr61-l2 antikoerper, zgc:158158 antikoerper, CYR61 antikoerper, AI325051 antikoerper, Igfbp10 antikoerper, cysteine rich angiogenic inducer 61 antikoerper, cysteine-rich, angiogenic inducer, 61 antikoerper, cysteine-rich, angiogenic inducer, 61 like 2 antikoerper, cysteine rich protein 61 antikoerper, cysteine rich angiogenic inducer 61 S homeolog antikoerper, CYR61 antikoerper, Cyr61 antikoerper, cyr61 antikoerper, cyr61l2 antikoerper, cyr61.S antikoerper

Hintergrund:

Description: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Gene: CYR61

Molekulargewicht: 42kDa

Gen-ID: 3491

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding