CLASP2 Antikörper
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- Target Alle CLASP2 Antikörper anzeigen
- CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CLASP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- CLASP2 Antibody detects endogenous levels of total CLASP2
- Kreuzreaktivität
- Human
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CLASP2
- Isotyp
- IgG
- Top Product
- Discover our top product CLASP2 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
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- Target
- CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
- Andere Bezeichnung
- CLASP2 (CLASP2 Produkte)
- Synonyme
- zgc:77279 antikoerper, DKFZp459M112 antikoerper, 1500004F14Rik antikoerper, 8030404L10Rik antikoerper, C77448 antikoerper, CLASP2beta antikoerper, mKIAA0627 antikoerper, cytoplasmic linker associated protein 2 antikoerper, CLIP associating protein 2 antikoerper, clasp2 antikoerper, CLASP2 antikoerper, Clasp2 antikoerper
- Hintergrund
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Description: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Gene: CLASP2
- Molekulargewicht
- 141kDa
- Gen-ID
- 23122
- UniProt
- O75122
- Pathways
- Microtubule Dynamics, Maintenance of Protein Location
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