CLASP2 Antikörper (AA 998-1026)

Produktnummer ABIN652978

Produktdetails anti-CLASP2 Antikörper

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Bindungsspezifität: AA 998-1026

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLASP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLASP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 998-1026 amino acids from human CLASP2.

Klon: RB16644

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CLASP2

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Andere Bezeichnung: CLASP2 (CLASP2 Produkte)

Synonyme: zgc:77279 antikoerper, DKFZp459M112 antikoerper, 1500004F14Rik antikoerper, 8030404L10Rik antikoerper, C77448 antikoerper, CLASP2beta antikoerper, mKIAA0627 antikoerper, cytoplasmic linker associated protein 2 antikoerper, CLIP associating protein 2 antikoerper, clasp2 antikoerper, CLASP2 antikoerper, Clasp2 antikoerper

Hintergrund: CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Molekulargewicht: 141064

Gen-ID: 23122

NCBI Accession: NP_001193973, NP_055912

UniProt: O75122

Pathways: Microtubule Dynamics, Maintenance of Protein Location