CISD2 Antikörper (Internal Region)

Produktnummer ABIN6260844

Produktdetails anti-CISD2 Antikörper

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CISD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: CISD2 Antibody detects endogenous levels of total CISD2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CISD2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Andere Bezeichnung: CISD2 (CISD2 Produkte)

Synonyme: ERIS antikoerper, Miner1 antikoerper, NAF-1 antikoerper, WFS2 antikoerper, ZCD2 antikoerper, 1500009M05Rik antikoerper, 1500026J14Rik antikoerper, 1500031D15Rik antikoerper, AI848398 antikoerper, B630006A20Rik antikoerper, Noxp70 antikoerper, Zcd2 antikoerper, RGD1566242 antikoerper, zgc:64148 antikoerper, eris antikoerper, miner1 antikoerper, wfs2 antikoerper, zcd2 antikoerper, cisd2 antikoerper, BcDNA:RE49709 antikoerper, Dmel\\CG1458 antikoerper, CDGSH iron sulfur domain 2 antikoerper, CDGSH iron sulfur domain 2 L homeolog antikoerper, CDGSH iron sulfur domain 2 S homeolog antikoerper, CISD2 antikoerper, Cisd2 antikoerper, cisd2 antikoerper, cisd2.L antikoerper, cisd2.S antikoerper

Hintergrund:

Description: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca2+ stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

Gene: CISD2

Molekulargewicht: 13-15 kDa

Gen-ID: 493856

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response