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CD86 Antikörper (Internal Region)

CD86 Reaktivität: Human, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6276600
  • Target Alle CD86 Antikörper anzeigen
    CD86
    Bindungsspezifität
    • 16
    • 9
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 149
    • 126
    • 54
    • 20
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    Human, Maus
    Wirt
    • 83
    • 78
    • 78
    Kaninchen
    Klonalität
    • 177
    • 59
    • 1
    Polyklonal
    Konjugat
    • 87
    • 25
    • 19
    • 16
    • 14
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD86 Antikörper ist unkonjugiert
    Applikation
    • 163
    • 100
    • 49
    • 42
    • 39
    • 38
    • 31
    • 24
    • 16
    • 16
    • 16
    • 14
    • 13
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    CD86 Antibody detects endogenous levels of total CD86.
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CD86, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product CD86 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    CD86
    Andere Bezeichnung
    CD86 (CD86 Produkte)
    Synonyme
    B7-2 antikoerper, B7.2 antikoerper, B70 antikoerper, CD28LG2 antikoerper, LAB72 antikoerper, B7 antikoerper, CLS1 antikoerper, Cd28l2 antikoerper, ETC-1 antikoerper, Ly-58 antikoerper, Ly58 antikoerper, MB7 antikoerper, MB7-2 antikoerper, TS/A-2 antikoerper, CD86 molecule antikoerper, CD86 antigen antikoerper, integrin subunit alpha 2b antikoerper, CD86 antikoerper, Cd86 antikoerper, Itga2b antikoerper
    Hintergrund

    Description: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

    Gene: CD86

    Molekulargewicht
    38kDa
    Gen-ID
    942
    UniProt
    P42081
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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