BIM Antikörper (N-Term)
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- Target Alle BIM (BCL2L11) Antikörper anzeigen
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BIM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Spezifität
- Bim Antibody detects endogenous levels of total Bim.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Bim, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product BCL2L11 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
- Andere Bezeichnung
- BCL2L11 (BCL2L11 Produkte)
- Synonyme
- bim antikoerper, BAM antikoerper, BIM antikoerper, BOD antikoerper, 1500006F24Rik antikoerper, Bim antikoerper, Bod antikoerper, BimL antikoerper, BIMEL antikoerper, BCL2-like 11 antikoerper, BCL2 like 11 antikoerper, BCL2-like 11 (apoptosis facilitator) antikoerper, bcl2l11 antikoerper, BCL2L11 antikoerper, Bcl2l11 antikoerper
- Hintergrund
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Description: Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
Gene: BCL2L11
- Molekulargewicht
- 22 kDa
- Gen-ID
- 10018
- UniProt
- O43521
- Pathways
- PI3K-Akt Signalweg, Neurotrophin Signalübertragung, Tube Formation, Positive Regulation of Endopeptidase Activity
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